Inhibition of MEK/ERK signalling pathway promotes erythroid differentiation and reduces HSCs engraftment in ex vivo expanded haematopoietic stem cells

The MEK/ERK pathway is found to be important in regulating different biological processes such as proliferation, differentiation and survival in a wide variety of cells. However, its role in self‐renewal of haematopoietic stem cells is controversial and remains to be clarified. The aim of this study...

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Detalles Bibliográficos
Autores principales: Zarrabi, Morteza, Afzal, Elaheh, Asghari, Mohammad Hossein, Mohammad, Monireh, Es, Hamidreza Aboulkheyr, Ebrahimi, Marzieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824365/
https://www.ncbi.nlm.nih.gov/pubmed/28994199
http://dx.doi.org/10.1111/jcmm.13379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824365/
https://www.ncbi.nlm.nih.gov/pubmed/28994199
http://dx.doi.org/10.1111/jcmm.13379

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