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Mammalian target of rapamycin inhibition attenuates myocardial ischaemia–reperfusion injury in hypertrophic heart

Pathological cardiac hypertrophy aggravated myocardial infarction and is causally related to autophagy dysfunction and increased oxidative stress. Rapamycin is an inhibitor of serine/threonine kinase mammalian target of rapamycin (mTOR) involved in the regulation of autophagy as well as oxidative/ni...

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Detalles Bibliográficos
Autores principales: Ma, Lei‐Lei, Ma, Xin, Kong, Fei‐Juan, Guo, Jun‐Jie, Shi, Hong‐Tao, Zhu, Jian‐Bing, Zou, Yun‐Zeng, Ge, Jun‐Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824378/
https://www.ncbi.nlm.nih.gov/pubmed/29314656
http://dx.doi.org/10.1111/jcmm.13451