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Down‐regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP‐2 and inducing mesenchymal‐to‐epithelial transition

Vasculogenic mimicry (VM) constitutes a novel approach for tumour blood supply and contributes to tumour metastasis and poor prognosis in patients with melanoma. Myoferlin (MYOF), a type II membrane protein involved in membrane regeneration and repair, is elevated in several malignant tumours, espec...

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Detalles Bibliográficos
Autores principales: Zhang, Wenxue, Zhou, Ping, Meng, Ai, Zhang, Rongxin, Zhou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824422/
https://www.ncbi.nlm.nih.gov/pubmed/29164766
http://dx.doi.org/10.1111/jcmm.13455