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Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury

BACKGROUND: Spinal cord injury (SCI) is a devastating condition mainly deriving from a traumatic damage of the spinal cord (SC). Immune cells and endogenous SC-neural stem cells (SC-NSCs) play a critical role in wound healing processes, although both are ineffective to completely restore tissue func...

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Detalles Bibliográficos
Autores principales: Cusimano, Melania, Brambilla, Elena, Capotondo, Alessia, De Feo, Donatella, Tomasso, Antonio, Comi, Giancarlo, D’Adamo, Patrizia, Muzio, Luca, Martino, Gianvito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824446/
https://www.ncbi.nlm.nih.gov/pubmed/29475438
http://dx.doi.org/10.1186/s12974-018-1085-9