Downregulation of microRNA-448 inhibits IL-1β-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3

BACKGROUND: Osteoarthritis is characterized by the continuous degradation of the articular cartilage. The microRNA miR-448 has been found to be broadly involved in cellular processes, including proliferation, apoptosis, invasion and EMT. While aberrant expression of miR-448 has been found in multipl...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hao, Wu, Di, Li, Hua, Chen, Nan, Shang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824452/
https://www.ncbi.nlm.nih.gov/pubmed/29483929
http://dx.doi.org/10.1186/s11658-018-0072-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824452/
https://www.ncbi.nlm.nih.gov/pubmed/29483929
http://dx.doi.org/10.1186/s11658-018-0072-6

Ejemplares similares