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Downregulation of microRNA-448 inhibits IL-1β-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3

BACKGROUND: Osteoarthritis is characterized by the continuous degradation of the articular cartilage. The microRNA miR-448 has been found to be broadly involved in cellular processes, including proliferation, apoptosis, invasion and EMT. While aberrant expression of miR-448 has been found in multipl...

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Detalles Bibliográficos
Autores principales:	Yang, Hao, Wu, Di, Li, Hua, Chen, Nan, Shang, Yongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824452/ https://www.ncbi.nlm.nih.gov/pubmed/29483929 http://dx.doi.org/10.1186/s11658-018-0072-6

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