Cargando…

LGR5 overexpression confers poor relapse-free survival in breast cancer patients

BACKGROUND: Cancer stem cells (CSCs) are believed to promote the malignant transformation of breast cancer via multiple signaling pathways, including the Wnt/β-catenin pathway. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) has been identified as a CSC-associated Wnt-regulated ta...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Ming-Feng, Chen, Po-Ming, Chu, Pei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824537/
https://www.ncbi.nlm.nih.gov/pubmed/29471794
http://dx.doi.org/10.1186/s12885-018-4018-1