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LGR5 overexpression confers poor relapse-free survival in breast cancer patients

BACKGROUND: Cancer stem cells (CSCs) are believed to promote the malignant transformation of breast cancer via multiple signaling pathways, including the Wnt/β-catenin pathway. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) has been identified as a CSC-associated Wnt-regulated ta...

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Detalles Bibliográficos
Autores principales:	Hou, Ming-Feng, Chen, Po-Ming, Chu, Pei-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824537/ https://www.ncbi.nlm.nih.gov/pubmed/29471794 http://dx.doi.org/10.1186/s12885-018-4018-1

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