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Insulin receptor sensitization restores neocortical excitation/inhibition balance in a mouse model of autism

BACKGROUND: Met receptor tyrosine kinase regulates neurogenesis, differentiation, migration, connectivity, and synaptic plasticity. The human Met gene has been identified as a prominent risk factor for autism spectrum disorder (ASD). Met gene-altered mice serve as useful models for mechanistic studi...

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Detalles Bibliográficos
Autores principales: Lo, Fu-Sun, Erzurumlu, Reha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824550/
https://www.ncbi.nlm.nih.gov/pubmed/29484150
http://dx.doi.org/10.1186/s13229-018-0196-6