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Insulin receptor sensitization restores neocortical excitation/inhibition balance in a mouse model of autism
BACKGROUND: Met receptor tyrosine kinase regulates neurogenesis, differentiation, migration, connectivity, and synaptic plasticity. The human Met gene has been identified as a prominent risk factor for autism spectrum disorder (ASD). Met gene-altered mice serve as useful models for mechanistic studi...
Autores principales: | Lo, Fu-Sun, Erzurumlu, Reha S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824550/ https://www.ncbi.nlm.nih.gov/pubmed/29484150 http://dx.doi.org/10.1186/s13229-018-0196-6 |
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