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Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules
BACKGROUND: In sharks, chickens, rats, frogs, medaka and zebrafish there is haplotypic variation in MHC class I and closely linked genes involved in antigen processing, peptide translocation and peptide loading. At least in chicken, such MHCIa haplotypes of MHCIa, TAP2 and Tapasin are shown to influ...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824609/ https://www.ncbi.nlm.nih.gov/pubmed/29471808 http://dx.doi.org/10.1186/s12862-018-1138-9 |