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Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules

BACKGROUND: In sharks, chickens, rats, frogs, medaka and zebrafish there is haplotypic variation in MHC class I and closely linked genes involved in antigen processing, peptide translocation and peptide loading. At least in chicken, such MHCIa haplotypes of MHCIa, TAP2 and Tapasin are shown to influ...

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Detalles Bibliográficos
Autor principal:	Grimholt, Unni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824609/ https://www.ncbi.nlm.nih.gov/pubmed/29471808 http://dx.doi.org/10.1186/s12862-018-1138-9

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