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An efficient preparation of labelling precursor of [(11)C]L-deprenyl-D(2) and automated radiosynthesis

BACKGROUND: The synthesis of [(11)C]L-deprenyl-D(2) for imaging of astrocytosis with positron emission tomography (PET) in neurodegenerative diseases has been previously reported. [(11)C]L-deprenyl-D(2) radiosynthesis requires a precursor, L-nordeprenyl-D(2), which has been previously synthesized fr...

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Detalles Bibliográficos
Autores principales: Zirbesegger, Kevin, Buccino, Pablo, Kreimerman, Ingrid, Engler, Henry, Porcal, Williams, Savio, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824701/
https://www.ncbi.nlm.nih.gov/pubmed/29503851
http://dx.doi.org/10.1186/s41181-017-0029-5