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Improving the stability of (11)C–labeled L-methionine with ascorbate

BACKGROUND: Carbon-11 labeled L-methionine ((11)C–MET) is a popular tracer used in the clinic for imaging brain tumors with positron emission tomography. However, the stability of (11)C–MET in its final formulation is not well documented in literature. Recently, we observed fast degradation of HPLC-...

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Detalles Bibliográficos
Autores principales: Woods, Michael, Leung, Leo, Frantzen, Kari, Garrick, Jennifer G., Zhang, Zhengxing, Zhang, Chengcheng, English, Wade, Wilson, Don, Bénard, François, Lin, Kuo-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824703/
https://www.ncbi.nlm.nih.gov/pubmed/29503854
http://dx.doi.org/10.1186/s41181-017-0032-x