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Convergent synthesis of (13)N-labelled Peptidic structures using aqueous [(13)N]NH(3)

BACKGROUND: Nitrogen-13 has a 10-min half-life which places time constraints on the complexity of viable synthetic methods for its incorporation into PET imaging agents. In exploring ways to overcome this limitation, we have used the Ugi reaction to develop a rapid one-pot method for radiolabelling...

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Detalles Bibliográficos
Autores principales: Blower, Julia E., Cousin, Samuel F., Gee, Antony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824707/
https://www.ncbi.nlm.nih.gov/pubmed/29503857
http://dx.doi.org/10.1186/s41181-017-0035-7