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Metabolite profiling with HPLC-ICP-MS as a tool for in vivo characterization of imaging probes

BACKGROUND: Current analytical methods for characterizing pharmacokinetic and metabolic properties of positron emission tomography (PET) and single photon emission computed tomography (SPECT) probes are limited. Alternative methods to study tracer metabolism are needed. The study objective was to as...

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Detalles Bibliográficos
Autores principales: Boros, Eszter, Pinkhasov, Omar R., Caravan, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824709/
https://www.ncbi.nlm.nih.gov/pubmed/29503859
http://dx.doi.org/10.1186/s41181-017-0037-5