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Intrinsically Disordered Regions Can Contribute Promiscuous Interactions to RNP Granule Assembly

Eukaryotic cells contain large RNA-protein assemblies referred to as RNP granules, whose assembly is promoted by both traditional protein interactions and intrinsically disordered protein domains. Using RNP granules as an example, we provide evidence for an assembly mechanism of large cellular struc...

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Detalles Bibliográficos
Autores principales: Protter, David S.W., Rao, Bhalchandra S., Van Treeck, Briana, Lin, Yuan, Mizoue, Laura, Rosen, Michael K., Parker, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824733/
https://www.ncbi.nlm.nih.gov/pubmed/29425497
http://dx.doi.org/10.1016/j.celrep.2018.01.036