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The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema

Emphysema is characterized by irreversibly enlarged airspaces and destruction of alveolar walls. One of the factors contributing to this disease pathogenesis is an elevation in extracellular matrix (ECM) degradation in the lung. Alveolar type II (ATII) cells produce and secrete pulmonary surfactants...

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Detalles Bibliográficos
Autores principales: Tan, Li Hui, Bahmed, Karim, Lin, Chih-Ru, Marchetti, Nathaniel, Bolla, Sudhir, Criner, Gerard J., Kelsen, Steven, Madesh, Muniswamy, Kosmider, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824795/
https://www.ncbi.nlm.nih.gov/pubmed/29476075
http://dx.doi.org/10.1038/s41598-018-21790-3