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Low-level Gestational Lead Exposure Alters Dendritic Spine Plasticity in the Hippocampus and Reduces Learning and Memory in Rats

Lead (Pb) is known to impair children’s cognitive function. It has been previously shown that developmental Pb exposure alters dendritic spine formation in hippocampal pyramidal neurons. However, the underlying mechanism has not yet been defined. In this study, a low-level gestational Pb exposure (G...

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Detalles Bibliográficos
Autores principales: Zhao, Zai-Hua, Zheng, Gang, Wang, Tao, Du, Ke-jun, Han, Xiao, Luo, Wen-Jing, Shen, Xue-Feng, Chen, Jing-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824819/
https://www.ncbi.nlm.nih.gov/pubmed/29476096
http://dx.doi.org/10.1038/s41598-018-21521-8