Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective

High-throughput screening (HTS) is a proven method for discovering new lead matter for drug discovery and chemical biology. To maximize the likelihood of identifying genuine binders to a molecular target, and avoid wasting resources following up compounds with unproductive/nonspecific mechanisms of...

Descripción completa

Detalles Bibliográficos
Autores principales: Rainard, Julie M., Pandarakalam, George C., McElroy, Stuart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824829/
https://www.ncbi.nlm.nih.gov/pubmed/29460707
http://dx.doi.org/10.1177/2472555217744728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824829/
https://www.ncbi.nlm.nih.gov/pubmed/29460707
http://dx.doi.org/10.1177/2472555217744728

Ejemplares similares