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Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective

High-throughput screening (HTS) is a proven method for discovering new lead matter for drug discovery and chemical biology. To maximize the likelihood of identifying genuine binders to a molecular target, and avoid wasting resources following up compounds with unproductive/nonspecific mechanisms of...

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Detalles Bibliográficos
Autores principales:	Rainard, Julie M., Pandarakalam, George C., McElroy, Stuart P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824829/ https://www.ncbi.nlm.nih.gov/pubmed/29460707 http://dx.doi.org/10.1177/2472555217744728

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