Allopurinol partially prevents disuse muscle atrophy in mice and humans

Disuse muscle wasting will likely affect everyone in his or her lifetime in response to pathologies such as joint immobilization, inactivity or bed rest. There are no good therapies to treat it. We previously found that allopurinol, a drug widely used to treat gout, protects muscle damage after exha...

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Detalles Bibliográficos
Autores principales: Ferrando, Beatriz, Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Puchades, Carlos, Derbré, Frederic, Gratas-Delamarche, Arlette, Laparre, Ludovic, Olaso-Gonzalez, Gloria, Cerda, Miguel, Viosca, Enrique, Alabajos, Ana, Sebastiá, Vicente, Alberich-Bayarri, Angel, García-Castro, Fabio, Viña, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824846/
https://www.ncbi.nlm.nih.gov/pubmed/29476130
http://dx.doi.org/10.1038/s41598-018-21552-1