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Allopurinol partially prevents disuse muscle atrophy in mice and humans
Disuse muscle wasting will likely affect everyone in his or her lifetime in response to pathologies such as joint immobilization, inactivity or bed rest. There are no good therapies to treat it. We previously found that allopurinol, a drug widely used to treat gout, protects muscle damage after exha...
Autores principales: | Ferrando, Beatriz, Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Puchades, Carlos, Derbré, Frederic, Gratas-Delamarche, Arlette, Laparre, Ludovic, Olaso-Gonzalez, Gloria, Cerda, Miguel, Viosca, Enrique, Alabajos, Ana, Sebastiá, Vicente, Alberich-Bayarri, Angel, García-Castro, Fabio, Viña, Jose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824846/ https://www.ncbi.nlm.nih.gov/pubmed/29476130 http://dx.doi.org/10.1038/s41598-018-21552-1 |
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