Hypothalamic ER–associated degradation regulates POMC maturation, feeding, and age-associated obesity

Pro-opiomelanocortin (POMC) neurons function as key regulators of metabolism and physiology by releasing prohormone-derived neuropeptides with distinct biological activities. However, our understanding of early events in prohormone maturation in the ER remains incomplete. Highlighting the significan...

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Detalles Bibliográficos
Autores principales: Kim, Geun Hyang, Shi, Guojun, Somlo, Diane R.M., Haataja, Leena, Song, Soobin, Long, Qiaoming, Nillni, Eduardo A., Low, Malcolm J., Arvan, Peter, Myers, Martin G., Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824855/
https://www.ncbi.nlm.nih.gov/pubmed/29457782
http://dx.doi.org/10.1172/JCI96420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824855/
https://www.ncbi.nlm.nih.gov/pubmed/29457782
http://dx.doi.org/10.1172/JCI96420

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