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A family of unconventional deubiquitinases with modular chain specificity determinants

Deubiquitinating enzymes (DUBs) regulate ubiquitin signaling by trimming ubiquitin chains or removing ubiquitin from modified substrates. Similar activities exist for ubiquitin-related modifiers, although the enzymes involved are usually not related. Here, we report human ZUFSP (also known as ZUP1 a...

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Detalles Bibliográficos
Autores principales: Hermanns, Thomas, Pichlo, Christian, Woiwode, Ilka, Klopffleisch, Karsten, Witting, Katharina F., Ovaa, Huib, Baumann, Ulrich, Hofmann, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824887/
https://www.ncbi.nlm.nih.gov/pubmed/29476094
http://dx.doi.org/10.1038/s41467-018-03148-5