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An all-trans-retinal-binding opsin peropsin as a potential dark-active and light-inactivated G protein-coupled receptor

Peropsin or retinal pigment epithelium-derived rhodopsin homolog, found in many animals, belongs to the opsin family. Most opsins bind to 11-cis-retinal as a chromophore and act as light-activated G protein-coupled receptors. Some peropsins, however, bind all-trans-retinal and isomerise it into 11-c...

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Detalles Bibliográficos
Autores principales: Nagata, Takashi, Koyanagi, Mitsumasa, Lucas, Robert, Terakita, Akihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824942/
https://www.ncbi.nlm.nih.gov/pubmed/29476064
http://dx.doi.org/10.1038/s41598-018-21946-1