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An all-trans-retinal-binding opsin peropsin as a potential dark-active and light-inactivated G protein-coupled receptor
Peropsin or retinal pigment epithelium-derived rhodopsin homolog, found in many animals, belongs to the opsin family. Most opsins bind to 11-cis-retinal as a chromophore and act as light-activated G protein-coupled receptors. Some peropsins, however, bind all-trans-retinal and isomerise it into 11-c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824942/ https://www.ncbi.nlm.nih.gov/pubmed/29476064 http://dx.doi.org/10.1038/s41598-018-21946-1 |