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Profiling Atlantic salmon B cell populations: CpG-mediated TLR-ligation enhances IgM secretion and modulates immune gene expression

While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs in magnet...

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Detalles Bibliográficos
Autores principales: Jenberie, Shiferaw, Thim, Hanna L., Sunyer, J. Oriol, Skjødt, Karsten, Jensen, Ingvill, Jørgensen, Jorunn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824956/
https://www.ncbi.nlm.nih.gov/pubmed/29476080
http://dx.doi.org/10.1038/s41598-018-21895-9