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Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism

BACKGROUND: Venous thromboembolism (VTE) is a major cause of morbidity and mortality in elderly patients. Extracellular DNA is a pro-inflammatory and pro-thrombotic mediator in vitro and in animal models. Levels of circulating extracellular DNA (ceDNA) are increased in VTE patients, but the associat...

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Detalles Bibliográficos
Autores principales: Jiménez-Alcázar, Miguel, Limacher, Andreas, Panda, Rachita, Méan, Marie, Bitterling, Josephine, Peine, Sven, Renné, Thomas, Beer, Jürg H., Aujesky, Drahomir, Lämmle, Bernhard, Fuchs, Tobias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825008/
https://www.ncbi.nlm.nih.gov/pubmed/29474368
http://dx.doi.org/10.1371/journal.pone.0191150