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Phenyl sulfate, indoxyl sulfate and p-cresyl sulfate decrease glutathione level to render cells vulnerable to oxidative stress in renal tubular cells

In chronic kidney disease patients, oxidative stress is generally associated with disease progression and pathogenesis of its comorbidities. Phenyl sulfate is a protein-bound uremic solute, which accumulates in chronic kidney disease patients, but little is known about its nature. Although many repo...

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Detalles Bibliográficos
Autores principales: Edamatsu, Takeo, Fujieda, Ayako, Itoh, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825083/
https://www.ncbi.nlm.nih.gov/pubmed/29474405
http://dx.doi.org/10.1371/journal.pone.0193342