Cerebrospinal fluid sCD27 levels indicate active T cell-mediated inflammation in premanifest Huntington's disease

INTRODUCTION: Huntington’s disease (HD) is a neurodegenerative disorder, but evidence also suggests neuroinflammation in the pathogenesis. The immune mechanisms involved and the timing of their activation need further clarification. METHODS: A clinically well-characterized HD cohort and gene negativ...

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Detalles Bibliográficos
Autores principales: Niemelä, Valter, Burman, Joachim, Blennow, Kaj, Zetterberg, Henrik, Larsson, Anders, Sundblom, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825143/
https://www.ncbi.nlm.nih.gov/pubmed/29474427
http://dx.doi.org/10.1371/journal.pone.0193492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825143/
https://www.ncbi.nlm.nih.gov/pubmed/29474427
http://dx.doi.org/10.1371/journal.pone.0193492

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