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Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type Ca(V)3.3 channels

Voltage-gated calcium channels contain four highly conserved transmembrane helices known as S4 segments that exhibit a positively charged residue every third position, and play the role of voltage sensing. Nonetheless, the activation range between high-voltage (HVA) and low-voltage (LVA) activated c...

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Detalles Bibliográficos
Autores principales: Sanchez-Sandoval, Ana Laura, Herrera Carrillo, Zazil, Díaz Velásquez, Clara Estela, Delgadillo, Dulce María, Rivera, Heriberto Manuel, Gomora, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825144/
https://www.ncbi.nlm.nih.gov/pubmed/29474447
http://dx.doi.org/10.1371/journal.pone.0193490