Cargando…
Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type Ca(V)3.3 channels
Voltage-gated calcium channels contain four highly conserved transmembrane helices known as S4 segments that exhibit a positively charged residue every third position, and play the role of voltage sensing. Nonetheless, the activation range between high-voltage (HVA) and low-voltage (LVA) activated c...
Autores principales: | Sanchez-Sandoval, Ana Laura, Herrera Carrillo, Zazil, Díaz Velásquez, Clara Estela, Delgadillo, Dulce María, Rivera, Heriberto Manuel, Gomora, Juan Carlos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825144/ https://www.ncbi.nlm.nih.gov/pubmed/29474447 http://dx.doi.org/10.1371/journal.pone.0193490 |
Ejemplares similares
-
Linker flexibility of IVS3-S4 loops modulates voltage-dependent activation of L-type Ca(2+) channels
por: Liu, Nan, et al.
Publicado: (2016) -
Nonsensing residues in S3–S4 linker’s C terminus affect the voltage sensor set point in K(+) channels
por: Carvalho-de-Souza, Joao L., et al.
Publicado: (2018) -
The Tarantula Toxin ω-Avsp1a Specifically Inhibits Human Ca(V)3.1 and Ca(V)3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor
por: Herzig, Volker, et al.
Publicado: (2022) -
3,3′-Dinitro-4,4′-bipyridine
por: Wang, Yong, et al.
Publicado: (2011) -
Role of individual S4 segments in gating of Ca(v)3.1 T-type calcium channel by voltage
por: Jurkovicova-Tarabova, Bohumila, et al.
Publicado: (2018)