Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

B cell follicles in secondary lymphoid tissues represent an immune privileged sanctuary for AIDS viruses, in part because cytotoxic CD8(+) T cells are mostly excluded from entering the follicles that harbor infected T follicular helper (T(FH)) cells. We studied the effects of native heterodimeric IL...

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Detalles Bibliográficos
Autores principales: Watson, Dionysios C., Moysi, Eirini, Valentin, Antonio, Bergamaschi, Cristina, Devasundaram, Santhi, Fortis, Sotirios P., Bear, Jenifer, Chertova, Elena, Bess, Julian, Sowder, Ray, Venzon, David J., Deleage, Claire, Estes, Jacob D., Lifson, Jeffrey D., Petrovas, Constantinos, Felber, Barbara K., Pavlakis, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825155/
https://www.ncbi.nlm.nih.gov/pubmed/29474450
http://dx.doi.org/10.1371/journal.ppat.1006902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825155/
https://www.ncbi.nlm.nih.gov/pubmed/29474450
http://dx.doi.org/10.1371/journal.ppat.1006902

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