An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations

Simultaneous analysis of genetic associations with multiple phenotypes may reveal shared genetic susceptibility across traits (pleiotropy). For a locus exhibiting overall pleiotropy, it is important to identify which specific traits underlie this association. We propose a Bayesian meta-analysis appr...

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Detalles Bibliográficos
Autores principales: Majumdar, Arunabha, Haldar, Tanushree, Bhattacharya, Sourabh, Witte, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825176/
https://www.ncbi.nlm.nih.gov/pubmed/29432419
http://dx.doi.org/10.1371/journal.pgen.1007139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825176/
https://www.ncbi.nlm.nih.gov/pubmed/29432419
http://dx.doi.org/10.1371/journal.pgen.1007139

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