A kinase-dependent feedforward loop affects CREBB stability and long term memory formation

In Drosophila, long-term memory (LTM) requires the cAMP-dependent transcription factor CREBB, expressed in the mushroom bodies (MB) and phosphorylated by PKA. To identify other kinases required for memory formation, we integrated Trojan exons encoding T2A-GAL4 into genes encoding putative kinases an...

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Detalles Bibliográficos
Autores principales: Lee, Pei-Tseng, Lin, Guang, Lin, Wen-Wen, Diao, Fengqiu, White, Benjamin H, Bellen, Hugo J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825208/
https://www.ncbi.nlm.nih.gov/pubmed/29473541
http://dx.doi.org/10.7554/eLife.33007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825208/
https://www.ncbi.nlm.nih.gov/pubmed/29473541
http://dx.doi.org/10.7554/eLife.33007

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