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A kinase-dependent feedforward loop affects CREBB stability and long term memory formation
In Drosophila, long-term memory (LTM) requires the cAMP-dependent transcription factor CREBB, expressed in the mushroom bodies (MB) and phosphorylated by PKA. To identify other kinases required for memory formation, we integrated Trojan exons encoding T2A-GAL4 into genes encoding putative kinases an...
Autores principales: | Lee, Pei-Tseng, Lin, Guang, Lin, Wen-Wen, Diao, Fengqiu, White, Benjamin H, Bellen, Hugo J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825208/ https://www.ncbi.nlm.nih.gov/pubmed/29473541 http://dx.doi.org/10.7554/eLife.33007 |
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