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Disulfide bond mapping of Pfs25, a recombinant malaria transmission blocking vaccine candidate

A liquid chromatography tandem-mass spectrometry method was developed to map the eleven disulfide bonds in Pfs25, a malaria transmission-blocking vaccine candidate. The compact and complex nature of Pfs25 has led to difficulties in prior peptide mapping efforts. Here, we report confirmation of prope...

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Detalles Bibliográficos
Autores principales: Lee, Shwu-Maan, Plieskatt, Jordan, King, C. Richter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825383/
https://www.ncbi.nlm.nih.gov/pubmed/29162427
http://dx.doi.org/10.1016/j.ab.2017.11.009