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Disulfide bond mapping of Pfs25, a recombinant malaria transmission blocking vaccine candidate
A liquid chromatography tandem-mass spectrometry method was developed to map the eleven disulfide bonds in Pfs25, a malaria transmission-blocking vaccine candidate. The compact and complex nature of Pfs25 has led to difficulties in prior peptide mapping efforts. Here, we report confirmation of prope...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825383/ https://www.ncbi.nlm.nih.gov/pubmed/29162427 http://dx.doi.org/10.1016/j.ab.2017.11.009 |