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A branching morphogenesis program governs embryonic growth of the thyroid gland

The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ development, distinguishes Nkx2-1(+...

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Detalles Bibliográficos
Autores principales: Liang, Shawn, Johansson, Ellen, Barila, Guillermo, Altschuler, Daniel L., Fagman, Henrik, Nilsson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825846/
https://www.ncbi.nlm.nih.gov/pubmed/29361553
http://dx.doi.org/10.1242/dev.146829