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Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro

Cataracts cause vision loss and blindness by impairing the ability of the ocular lens to focus light onto the retina. Various cataract risk factors have been identified, including drug treatments, age, smoking and diabetes. However, the molecular events responsible for these different forms of catar...

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Detalles Bibliográficos
Autores principales: Murphy, Patricia, Kabir, Md Humayun, Srivastava, Tarini, Mason, Michele E., Dewi, Chitra U., Lim, Seakcheng, Yang, Andrian, Djordjevic, Djordje, Killingsworth, Murray C., Ho, Joshua W. K., Harman, David G., O'Connor, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825866/
https://www.ncbi.nlm.nih.gov/pubmed/29217756
http://dx.doi.org/10.1242/dev.155838