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Light-focusing human micro-lenses generated from pluripotent stem cells model lens development and drug-induced cataract in vitro
Cataracts cause vision loss and blindness by impairing the ability of the ocular lens to focus light onto the retina. Various cataract risk factors have been identified, including drug treatments, age, smoking and diabetes. However, the molecular events responsible for these different forms of catar...
Autores principales: | Murphy, Patricia, Kabir, Md Humayun, Srivastava, Tarini, Mason, Michele E., Dewi, Chitra U., Lim, Seakcheng, Yang, Andrian, Djordjevic, Djordje, Killingsworth, Murray C., Ho, Joshua W. K., Harman, David G., O'Connor, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825866/ https://www.ncbi.nlm.nih.gov/pubmed/29217756 http://dx.doi.org/10.1242/dev.155838 |
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