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The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival
Asna1, also known as TRC40, is implicated in the delivery of tail-anchored (TA) proteins into the endoplasmic reticulum (ER), in vesicle-mediated transport, and in chaperoning unfolded proteins during oxidative stress/ATP depletion. Here, we show that Asna1 inactivation in pancreatic progenitor cell...
Autores principales: | Norlin, Stefan, Parekh, Vishal, Edlund, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825870/ https://www.ncbi.nlm.nih.gov/pubmed/29180572 http://dx.doi.org/10.1242/dev.154468 |
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