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Hierarchical genetic interactions between FOXG1 and LHX2 regulate the formation of the cortical hem in the developing telencephalon

During forebrain development, a telencephalic organizer called the cortical hem is crucial for inducing hippocampal fate in adjacent cortical neuroepithelium. How the hem is restricted to its medial position is therefore a fundamental patterning issue. Here, we demonstrate that Foxg1-Lhx2 interactio...

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Detalles Bibliográficos
Autores principales: Godbole, Geeta, Shetty, Ashwin S., Roy, Achira, D'Souza, Leora, Chen, Bin, Miyoshi, Goichi, Fishell, Gordon, Tole, Shubha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825872/
https://www.ncbi.nlm.nih.gov/pubmed/29229772
http://dx.doi.org/10.1242/dev.154583