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Revealing age-related changes of adult hippocampal neurogenesis using mathematical models
New neurons are continuously generated in the dentate gyrus of the adult hippocampus. This continuous supply of newborn neurons is important to modulate cognitive functions. Yet the number of newborn neurons declines with age. Increasing Wnt activity upon loss of dickkopf 1 can counteract both the d...
Autores principales: | Ziebell, Frederik, Dehler, Sascha, Martin-Villalba, Ana, Marciniak-Czochra, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825879/ https://www.ncbi.nlm.nih.gov/pubmed/29229768 http://dx.doi.org/10.1242/dev.153544 |
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