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Activation of Astrocytes and Microglial Cells and CCL2/CCR2 Upregulation in the Dorsolateral and Ventrolateral Nuclei of Periaqueductal Gray and Rostral Ventromedial Medulla Following Different Types of Sciatic Nerve Injury

Peripheral nerve injuries (PNIs) may result in cellular and molecular changes in supraspinal structures possibly involved in neuropathic pain (NPP) maintenance. Activated glial cells in specific supraspinal subregions may affect the facilitatory role of descending pathways. Sterile chronic compressi...

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Detalles Bibliográficos
Autores principales: Dubový, Petr, Klusáková, Ilona, Hradilová-Svíženská, Ivana, Joukal, Marek, Boadas-Vaello, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825898/
https://www.ncbi.nlm.nih.gov/pubmed/29515373
http://dx.doi.org/10.3389/fncel.2018.00040