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A novel ocular delivery of brinzolamide based on gellan gum: in vitro and in vivo evaluation

BACKGROUND: The aim of the study was to develop a sustained ocular delivery of brinzolamide (BLZ) based on gellan gum. METHODS: The formulations were characterized for clarity, gelling capacity, rheological studies, pH, drug content, and in vitro drug-release behavior. In vivo rabbit eye irritation...

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Detalles Bibliográficos
Autores principales: Sun, Jingfen, Zhou, Zhengshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825998/
https://www.ncbi.nlm.nih.gov/pubmed/29503531
http://dx.doi.org/10.2147/DDDT.S153405