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A novel ocular delivery of brinzolamide based on gellan gum: in vitro and in vivo evaluation
BACKGROUND: The aim of the study was to develop a sustained ocular delivery of brinzolamide (BLZ) based on gellan gum. METHODS: The formulations were characterized for clarity, gelling capacity, rheological studies, pH, drug content, and in vitro drug-release behavior. In vivo rabbit eye irritation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825998/ https://www.ncbi.nlm.nih.gov/pubmed/29503531 http://dx.doi.org/10.2147/DDDT.S153405 |