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A ‘molecular guillotine’ reveals the interphase function of Kinesin-5
Motor proteins are important for transport and force generation in a variety of cellular processes and in morphogenesis. Here, we describe a general strategy for conditional motor mutants by inserting a protease cleavage site into the ‘neck’ between the head domain and the stalk of the motor protein...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826049/ https://www.ncbi.nlm.nih.gov/pubmed/29361546 http://dx.doi.org/10.1242/jcs.210583 |