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Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release

Devil facial tumor disease (DFTD) is renowned for its successful evasion of the host immune system. Down regulation of the major histocompatabilty complex class I molecule (MHC-I) on the DFTD cells is a primary mechanism of immune escape. Immunization trials on captive Tasmanian devils have previous...

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Detalles Bibliográficos
Autores principales: Pye, Ruth, Patchett, Amanda, McLennan, Elspeth, Thomson, Russell, Carver, Scott, Fox, Samantha, Pemberton, David, Kreiss, Alexandre, Baz Morelli, Adriana, Silva, Anabel, Pearse, Martin J., Corcoran, Lynn M., Belov, Katherine, Hogg, Carolyn J., Woods, Gregory M, Lyons, A. Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826075/
https://www.ncbi.nlm.nih.gov/pubmed/29515577
http://dx.doi.org/10.3389/fimmu.2018.00259