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Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release
Devil facial tumor disease (DFTD) is renowned for its successful evasion of the host immune system. Down regulation of the major histocompatabilty complex class I molecule (MHC-I) on the DFTD cells is a primary mechanism of immune escape. Immunization trials on captive Tasmanian devils have previous...
Autores principales: | Pye, Ruth, Patchett, Amanda, McLennan, Elspeth, Thomson, Russell, Carver, Scott, Fox, Samantha, Pemberton, David, Kreiss, Alexandre, Baz Morelli, Adriana, Silva, Anabel, Pearse, Martin J., Corcoran, Lynn M., Belov, Katherine, Hogg, Carolyn J., Woods, Gregory M, Lyons, A. Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826075/ https://www.ncbi.nlm.nih.gov/pubmed/29515577 http://dx.doi.org/10.3389/fimmu.2018.00259 |
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