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Persistent Expression of Serotonin Receptor 5b Alters Breathing Behavior in Male MeCP2 Knockout Mice

Mutations in the transcription factor methyl-CpG-binding protein 2 (MeCP2) cause the neurodevelopmental disorder Rett syndrome (RTT). Besides many other neurological problems, RTT patients show irregular breathing with recurrent apneas or breath-holdings. MeCP2-deficient mice, which recapitulate thi...

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Detalles Bibliográficos
Autores principales: Vogelgesang, Steffen, Niebert, Marcus, Bischoff, Anne M., Hülsmann, Swen, Manzke, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826236/
https://www.ncbi.nlm.nih.gov/pubmed/29515365
http://dx.doi.org/10.3389/fnmol.2018.00028